Monday, June 29, 2009

And I thought things were going well

Not 30 minutes after I arrived at work (post-IUI) I got a call from my nurse scheduling my beta and asking me to make a follow-up appointment with the RE to discuss the next step. Reminding me that this was our third IUI (really, second) and we needed to think about what to do next. WTF??? Evidently, this IUI was already considered to be a failure less than an hour after it was over. I'll admit we didn't get the best sample, the numbers were considerably lower than for the first IUI, but they were still in the range that was acceptable for IUI. Couldn't they have let me enjoy the post-coital glow (so to speak) for a little while before getting all doom and gloom on me?
And on a tangental note, what do I have to do to get them pronounce my name correctly when they call me? Seriously, if one more allegedly literate person calls me "Elsie" after reading my name from my chart, I'm going to explode. Honestly, does anyone actually name their children Elsie anymore? I just don't get how so many people can mess this up. Internets, don't name your daughters Elsie, it sounds like a cow. And if you name them Elise, put a "y" in it like the mom on Family Ties because there are a lot of morons out there who will transpose the "i" and "s" which will result in a lot of cringing for your undoubtedly lovely daughter.
And that's all I have to say right now.

Saturday, June 27, 2009

Your eggs are cooked

So said the ultrasound technician this morning after measuring my follicles. The left one is now 22 mm and the 3 on the right are 16, 16 & 17 mm. Ovadril tonight and the IUI is scheduled for Monday morning. Of course I have two meetings first thing Monday, fortunately I called both of them so I can easily move them to later in the day. Maybe I'm just more comfortable with the process, but I feel really good about this cycle. Fingers crossed.

Friday, June 26, 2009

Cautiously optimistic

Things appear to be progressing nicely, the follicle on the left is now 19 mm and there are now 3-13 mm follicles on the right, with my estradiol level up to 753. I am to take another 150 units of Gonal-F tonight and then go back in tomorrow morning for monitoring. When I pressed the nurse for more details (I'm getting much better at this) she said we are aiming for 3-4 follicles that are at least 16 mm in size and that she "wouldn't be surprised" if I used the trigger shot tomorrow night. I asked if the larger follicle on the left was problem and she said that it is likely to be re-absorbed and that we are really only working on the 3 on the right. I can't remember the exact details of our first IUI cycle, but I think we were in a similar boat with 4 follicles but one much larger than the others, except that time around using twice as much FSH. So far, so good.

In other news, I found the results of this study to be sobering. They were looking at the rate of live births in a cohort of women undergoing up to 6 cycles of IVF at a clinic in Massachusetts. In the paper they claim that they picked 6 cycles because Massachusetts has a mandate that fertility treatments must be covered by insurance, and that typical coverage in this state allows for 6 cycles. I live in this state and I definitely don't have enough coverage for six cycles of IVF: my insurance caps my coverage for fertility related treatment at a dollar amount that might pay for 2-3 IVF cycles, which is one of the reasons I insisted that we start with IUI (the main reason being that our doctor said we were good candidates). Anyway, the main findings were that the chance of having a pregnancy resulting in a live birth after six full cycles of IVF were between 65 and 86% for women under 35, but only 23-42% for women over 40. That's less than a 50% chance that I will take home a bio baby after a lot of treatment, much of it that will not be covered by insurance. I never really believed the statistics about the rapid decrease in fertility after the age of 35 because it just wasn't part of my life experience. My mom had a surprise pregnancy at age 37, one of my best friends just had her first baby at 40 after barely trying. I know their experiences don't mean anything for my odds, but hey, when you're not trying to get pregnant you really don't pay attention to these things.

I don't know how far I want to take this. Personally, when it comes down to whether or not I would pay out of pocket to continue trying to get pregnant after my insurance runs out, right now I don't feel inclined. Given my odds (I'll definitely be on the other side of 40 by then), I think I would rather spend the cash on adoption fees, assuming my husband is on board. Hopefully I won't have to make that choice, but hey, I like to be prepared.

Wednesday, June 24, 2009

CD8 by the numbers


3 measurable follicles: 2 on the right (11, 12 mm) and 1 on the left (15 mm)
2 more days of 150 units Gonal-F, then back on Friday for monitoring
1 last day of rain and cold before we see some sun

Sunday, June 21, 2009

One

I understand that many women in the throes of infertility are deeply irritated by the phrase "it only takes one." For me, "it only takes one" is a mantra that allows me to consider the possibility that I will win the baby lottery. The reality is that while one egg and one sperm do a baby make, it may never do so for me, and I have no control over whether it does. At 39 1/2 I am fully aware that my window for conception narrows every day. Honestly, I never thought I'd be in this position (who does, right?) but I happen to have good insurance and a top-notch clinic right down the street and when I realized how important it was to my husband to do everything possible to try to have a child that shared our genes, I shrugged and said I would try. Somehow in just six months we seem to have become deeply entrenched in a process that I know is more likely to fail than to succeed. And while I won't say that I'm ok with it, I do understand that the outcome is as out of my control as it is for any woman. Money and medical treatment can only increase my odds of getting pregnant by a small percentage, and in the end it will come down to a random collision of two cells that triggers a cascade of biological events that has the potential of resulting in a baby. Right now, it's enough hope to get me by.

Friday, June 19, 2009

And so, it begins

It's CD3 and I've taken my first hit of Gon.al-F, courtesy of my awesome husband who is always willing to help me out with the shots. Even though they're subcutaneous and via a superfine needle, I much prefer having him do the injections. Funny how we both find it so much easier to be the caregiver than the patient. Four more days of 150 units and then I go in for monitoring on Wednesday morning. I can't quite believe that this seems normal to me now, the hormones and the blood draws and ultrasounds.

Wednesday, June 17, 2009

As ready as I'll ever be


The consult with the anesthesiologist went well. I told him about my previous experience with conscious sedation and he said that there is a small percentage of people who become more anxious with these types of medications as opposed to relaxing. He told me what he plans to give me during my retrieval procedure, should it come to that, and assured me that he thought I would do well with the medications. I feel heard, if not yet totally comfortable with the idea of surgery. It was interesting to go visit the surgical area of the clinic. There were 6-8 women sitting in recovery bays and not one of them was crying hysterically, so that was good. I did get a little jittery, but at least I know what it looks like now.

After my consult I grabbed some lunch at a local fast food place and overheard a funny conversation. Two older women were finishing their meal and bemoaning the lack of full service gas stations. One said "I drove all the way from Massachusetts to Florida and didn't find one full service station; I had to get out of the car and do it myself every time. Next time, I'm taking the bus." Apparently sitting on a cramped bus for 20 hours is preferable to having to get out of your car a half dozen times to get gas? People are funny.

Game on

As anticipated, CD1 has arrived and we begin our last IUI attempt. Third time's the charm, right? At least I have the pleasure of driving to and from appointments in my shiny new (to-me) car. We ended up with a 2008 Hond@ CR-V and I think she and I are going to be great friends. It was a close contest between the CR-V and the T0y0t@ RAV4, but in the end I decided that the hatch-style rear door of the CR-V was going to work better for me. When we test-drove it I found a single Cheerio under the rear seat and took that as a good omen for this cycle. I've got my appointment with the anesthesiologist this morning, hopefully I come away from it reassured about my options if we get the point of IVF.

Hey, does anyone else use Tylenol for cramps? I am dutifully staying away from Advil, but don't think I can get through the next few days without some form of pain relief.

Monday, June 15, 2009

Waiting, waiting

CD1 should be right around the corner and I'm ready to get the IUI#3 party started. Meds are in the fridge (does anyone else store their trigger shot in the egg compartment? Ovadril, anyone?) and I have a consult with the anesthesiologist set up for Wednesday just in case we end up in a position where we need to convert the cycle. Now that I have a plan, and my preparations in place, I feel so much more confident. I hate the uncertainty of it all, you know? Having a road map forward is so helpful, even if all the streets aren't marked.

I just found out that one of my friends is pregnant and if ever I needed a reminder that I want a baby, this was it. I am so, so happy for her, she has had two miscarriages (one at 14 weeks) since her first baby and waited until well into her second trimester to announce this one. Baby boy #2 is due shortly after her son's third birthday so it's going to be a fun autumn around here. I need to get started knitting a baby blanket for the little guy. Sometimes I can get so bogged down in the process of ART that I forget that it's all about the wee babe to be, hopefully with my husband's dark eyes and my sweet disposition.

Sunday, June 14, 2009

Baby-friendly cars and other leaps of faith

We spent the weekend test-driving cars because I either need to spend a small fortune repairing my current one so that I don't die from carbon monoxide poisoning, or I need to replace it. Given that my car is 9 years old and has been having more and more frequent and expensive issues, I have opted to ditch it and buy a new (to me) one. I have a thing for station wagons, what can I say, I like to haul stuff. I'd like to upgrade to all wheel drive and the options for wagons in my price range are limited (I know there are a bazillion of them on the road, but I didn't love the Out6@ck I tried). Oh, Toyota, why can't you bring back the Corolla wagon, circa 1982?

Anyhow, we decided to expand our options and looked at small crossover SUVs since they are really just station wagons with a few more inches of head room. As the sales people went through the features, they inevitably asked if we were planning to expand our family, and then went on to talk about car seat tethers etc. Now, while we want to expand our family, given our ages and medical issues, the odds are pretty even that we won't. So, do I buy a car with good child seating options or not? If I choose the car with the most child-friendly features and we don't end up with a baby in a year will the damn car be a constant reminder of our fertility journey?

It's a decision that is requiring a certain leap of faith, at least on my part. Since we're unlikely to have our parental status decided by a spontaneous pregnancy, we've already had to put our desire to be parents out there by pursuing ART and, in doing so, putting metamorphic neon signs above our heads that scream "We're Trying to Have a Baby" to innumerable doctors, nurses, receptionists and insurance companies. It's just a little bit scary, declaring my intentions and being unsure of my body's ability to deliver on them. So, while I'm much more comfortable standing securely on the edge, peering over to observe danger from afar, leap I will.

Besides, I have to think of the resale value.

Thursday, June 11, 2009

We're all falling apart around here

I took the small cat to the vet last night for his thyroid re-check (he's been on medication for 4 years for hyperthyroidism) and casually mentioned that I didn't think he was seeing very well these days, and also that he seemed really needy and whiney. So, I really shouldn't have been surprised when Dr. Sarah checked him out and agreed that, yes, he's pretty much blind and that it is probably very confusing and upsetting to him, hence the constant demands for attention. She says he can see shadows, but not much else, and that it's likely the consequence of senile changes in his brain due to advanced age (he's 17). Poor little guy, he's always been such an outgoing and friendly cat, it's hard to see him decline like this. He's always been really great with kids, it's sad to think that he might not be around to play with our hypothetical future children.

CD1(-5ish) and counting down to the next IUI cycle. I'm going to meet with the anesthesiologist at my clinic next week to talk about some of my concerns regarding sedation so that I am prepared in case we need to convert this cycle. I've had conscious sedation in the past for medical procedures and h-a-t-e-d it; I woke up crying hysterically and it was very upsetting. Hopefully he/she can address my fears and I can figure out how to deal with the sedation/retrieval process if we have to go there.

IUI, IVF, I just don't know

I called my clinic yesterday to let them know I wanted to switch to IVF for my next cycle and was immediately overwhelmed. Apparently I'm supposed to have had a recent physical and current PAP??? You'd think someone would have mentioned that earlier, like when there was still time for me to make an appointment with my doctor. I tried my gyn, but she is booking physicals out to Sept/Oct and my internist out to Jan/Feb. I managed to get an appointment with the nurse practitioner who works with my internist for Friday, but I've never met her and it doesn't make me very happy - so much for continuity of care. I can't figure out if I have unrealistic expectations from my clinic/RE with regard to information and preparation, but I'm not happy. If I wasn't so daunted by the prospect of trying to find another clinic and waiting weeks for an initial consultation I would seriously consider switching doctors.

After talking to the admin at the clinic (lovely, warm woman) I started to freak out about my decision. IVF scares me and the fact that my clinic treats it as if it were no big deal scares me even more. I don't really want to undergo surgery and anesthesia, it's a big freaking deal to me. And, given our one shot at IUI, I don't feel like we've explored that option fully. I called my husband in a panic and he agreed to go back to our original plan of another IUI cycle. So, I called the admin back and told her I'd changed my mind and she was completely understanding about it.

The wait for CD1 continues, and I'll also get my physical out of the way and do the pre-op counseling just in case we are in a position where we need to switch to IVF and to be on-track to proceed with a full IVF cycle in August if need be.

Tuesday, June 9, 2009

Backstory: IUI#1 & #2

We finished our initial testing in November 2008 and tried to start an IUI cycle right around Thanksgiving but getting insurance approval, medications and pre-paid travel plans got in the way. Honestly, I wasn't mentally ready to start fertility treatments and needed some time to sit with the information. Then we had family visiting for four weeks in December/January and needed to recover. In February I started 350 units of Follistim on CD3 (through 9) and got to know the clinic's ultrasound technicians on a regular and intimate basis. Also, I made a mental note to start getting regular pedicures and bikini waxes even though it was the middle of one of the snowiest New England winters in recent memory. That flimsy paper sheet was doing nothing to maintain my aura of confidence, I tell you. But I digress. My ovaries responded perfectly and by trigger day I had three nice looking follicles ready for action. The day of the insemination was stressful. My husband did not appreciate having his "gentleman's time" with a plastic cup at 7 am but he soldiered on and we ended up with a normal specimen. I was too overwhelmed with everything going on to note the numbers, but apparently they were perfect for IUI.

Unfortunately, fourteen days later I was back to CD1. I never felt like it had worked so I wasn't at all surprised or disappointed (truthfully). We were geared up to try again right away, but when I had the pre-cycle testing done there was still a follicle hanging around and my doctor said we had to skip the month. I was crushed. Up to this point, I had been very cerebral about the process, but when I took the call from the nurse I was angry and frustrated for the first time. Twisted-gut-ball-of-fury-how-the-hell-did-this-happen-to-me angry and frustrated, to be precise. Yeah, reality check #1 was realizing that trying to get pregnant was going to be out of my control.

Reality check #2 was realizing that I was likely never going to actually see or talk to my doctor. We initially chose our clinic on recommendation and because it is very convenient to get to from both home and work. After my initial consultation it was as if my doctor no longer existed; I communicated only with the nurses. So, so frustrating as I am the type of person who really needs to develop trust with my health care providers in order to feel comfortable. It became apparent very quickly that I was just one of the thousands of people who file through this particular clinic every year and that cozy relationship I had envisioned with my caregivers involving me bringing in cookies and sending them photos of my (hypothetical future) babies was total fantasy.

So, we waited out the month and started another IUI cycle in April. Same dosage of Follistim and things were looking good, three follicles on CD5, right on schedule. Until my monitoring appointment on CD8 when the ultrasound technician (the young, slightly rough one) spent a lot of time clicking and asked "you're doing IVF, right?" Warning bells were tinkling faintly in the distance, but I told her no, I was on an IUI cycle. When she was done I sat up and she turned the computer screen around and showed me the nine perfect follicles she had counted. Yikes.
When the nurse left a message a couple of hours later confirming that I had too many follicles for IUI, she also told me that the doctor wanted me to switch to IVF. I called back and another nurse was covering for her and told me I had to decide Right Now! because she needed to call in more medications Today! and I'd have to mix something with the Follistim and take something else and one of them was going to be an IM injection* and never actually asked me if I was ok with it. Which I totally wasn't because we had never discussed switching mid-cycle. In fact, I had told my doctor during my one talk with her that I wasn't sure I wanted to have that level of intervention but clearly that wasn't written in my file anywhere. It didn't help my stress level that I had been slipping into empty conference rooms at work from to make all these phone calls and I was having an incredibly busy week at work and had a final exam in a few days. My husband managed to talk me down and agreed that there was no need to rush so I called the clinic back and cancelled the cycle. They were, shall I say, a little surprised. I had responded so well, it was a perfect situation for IVF, why wouldn't I disrupt my entire life for unplanned surgery in 3-5 days? I mean, really, my reproductive organs do not exist purely for them to do procedures on, and I didn' t like having to explain that.

Then in May, the timing was all wrong as my husband had to have surgery and my cycle was completely thrown off from the nine party-crashing follicles from the previous cycle, so we skipped another month. We spent the last month talking about our options, and even had a follow-up appointment with Dr. Frosty (even my husband thinks she is cold) who reminded us that our chances of getting pregnant via IUI were only ~12% and she would only recommend doing one more cycle before switching to IVF. So, here we sit won the brink of starting an invasive procedure that I never in my life thought I would elect to participate in. The most surprising thing? I think we're going to do it.

*All my medications had been subcutaneous and I my husband had been giving them to me. I freaked at the thought of having to have him or me figure out how to give me an intramuscular injection after work that day. Turns out the nurse covering the phone (not regular IUI nurse for my doctor) was wrong, and in fact the clinic hadn't used any IM injections in years. When I learned this I was pissed and even more frustrated with the communication channels.

Monday, June 8, 2009

How I got here, in 39 lines

  1. I am the reason my parents got married.
  2. My mom smoked cigars while she was pregnant with me.
  3. Eh, I turned out fine.
  4. My two youngest brothers (twins) were conceived while my mother was on the pill.
  5. I had a lot of responsibility as a child, especially after my parents separated.
  6. Like babysitting my brothers after school, making dinner and being my mom's best friend and confidante.
  7. On Saturdays my mom would drop me off at the grocery store with a list, the folder of coupons and blank check.
  8. This is not a life I recommend for an 11 year-old and I swore I would never, ever have children. 
  9. Although I still love grocery shopping.
  10. I have two aunts who failed to conceive for years, adopted, and then got pregnant.
  11. There are a lot of surprise pregnancies in my family.
  12. I had one of my own when I was 26.
  13. My boyfriend and I had just moved to the US and were living in two distant cities and commuting on weekends.
  14. The lack of maternity leave and high cost of daycare freaked me out.
  15. Honestly, my boyfriend was kind of an asshole, I just didn't realize it at the time.
  16. It really wasn't the right time to have a child.
  17. So I had an abortion.
  18. It's something I think about a lot, but I've never wanted to take it back.
  19. I met my husband at work and knew the moment I saw him that I wanted to marry him.
  20. Early in our relationship he offered to have fertility testing done because he saw the mother in me and didn't want me to marry someone who couldn't give me children.
  21. It was incredibly sweet and touching but I declined because he was way too sexy to be infertile.
  22. I really didn't want to get pregnant before we were married so we didn't start trying until after the wedding.
  23. A year later he went in for testing.
  24. Motility and morphology were abnormal.
  25. His doctor suggested IUI so I found a clinic near work and made an appointment.
  26. I was floored when my ovaries failed the Clomid challenge.
  27. I suggested adoption but my husband isn't ready.
  28. After a lot of research on adoption I'm not sure I'm ready either.
  29. So we decided to try medicated IUI.
  30. Round one was textbook perfect but didn't get us pregnant.
  31. We had to sit out a month because of a follicle that refused to leave the party on time.
  32. Round two started out fine but resulted in 9 follicles by day 8.
  33. My doctor suggested switching to IVF but I've only met her once in 6 months and don't really feel like I want to embark on an incredibly invasive procedure at the drop of a hat.
  34. One of my best friends from high school got pregnant on her first try last year.
  35. She brought the baby to her 40th birthday party: he's gorgeous.
  36. I haven't told her we're using fertility treatments, she wouldn't understand.
  37. Until very recently, I know I wouldn't have.
  38. But I don't begrudge her, or anyone else, their babies.
  39. I just want one of my own.